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White or almost white powder.Soluble in acids and alkalis;insoluble in water, alcohol and ether.Odorless, tasteless, easily deteriorates upon exposure to light, decomposes in boiling water.
In the pharmaceutical field, bismuth subsalicylate is employed as an active pharmaceutical ingredient (API) for bismuth-based formulations such as bismuth subsalicylate dry suspension and bismuth subsalicylate tablets, commonly used to treat diarrhea, indigestion, gastric ulcers and duodenal ulcers. In the industrial field, it can be used as a catalyst in cathodic electrophoretic coatings.
| Bismuth Subsalicylate(USP) | Bismuth Subsalicylate(EUROPEAN PH.) | ||
|---|---|---|---|
| Determinations | Specifications | Determinations | Specifications |
| Appearance | Fine to off-white | Appearance | Fine to off-white |
| Solubility | Test | Solubility | Practically insoluble in water and alcohol |
| Identification | A.IR | Identification | A.Salicylate Complies |
| B.Bismuth | B.Bismuth Complies | ||
| pH | 2.7-5.0 | Acidity | Test |
| Loss on Drying | ≤1.0% | Bismuth Content(ODB) | 56.0-59.4% |
| Nitrates | ≤0.4% | Chloride | ≤200ppm |
| As | ≤10ppm | Nitrates | ≤0.4% |
| Free Salicylic Acid | ≤0.2% | Ag | ≤25ppm |
| Cu | ≤10ppm | Cu | ≤50ppm |
| Pb | ≤10ppm | Pb | ≤20ppm |
| Ag | ≤10ppm | Soluble Bismuth | ≤40ppm |
| Soluble Bismuth | ≤40ppm | Loss on Drying | ≤1.0% |
| Bismuth Content(ODB) | 56.0-59.4% | ||
| Total Salicylic Acid Content (Dry Basis) | 36.5-39.3% | ||